Bellafill®, previously known as Artefill, is a dermal filler that has been FDA-approved for the correction of nasolabial folds around the nose and mouth since 2006. While most dermal fillers are comprised of hyaluronic acid, Bellafill® is a unique formulation of polymethylmethacrylate (PMMA) collagen microspheres that provide both instant and long-lasting improvement to the visible signs of aging. It is comprised of 20% PMMA microspheres and 80% collagen. This unique makeup is also the reason why it is the only dermal filler approved to treat acne scars.

Once injected directly underneath the skin of the treatment areas, it is formulated to immediately smooth and tighten the skin during the very first treatment. The PMMA microspheres are between 30-50 microns in size, which means that they are almost imperceptible to the human eye. Once the PMMA microspheres are injected, they remain in place and create a matrix. The collagen that comprises Bellafill® will slowly be absorbed, but the microspheres will not. The matrix created by the microspheres will support the production of new collagen – the protein in your skin that is responsible for its strength and structure. In this way, you are provided with younger looking, beautiful skin and contour that lasts.


While some dermal fillers wear off as soon as four months after treatment, Bellafill® has been proven to create a long-lasting collagen matrix as well as new blood vessels to increase circulation and add a youthful, long-lasting glow to the skin for 5 years, sometimes longer.

Bellafill® has been extensively studied longer than any other dermal filler, and has results that last for up to five years for wrinkle correction and up to one year for acne scar correction.

In addition to filling in the nasolabial folds, Bellafill® is also commonly used to reduce the appearance of acne scars.

Bellafill® provides the longest lasting wrinkle reduction without the need for surgery or an invasive procedure.


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